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Type III Site-Specific DNase

《英文msh詞典》Type III Site-Specific DNase
[入口詞] Type III Site-Specific DNase
[主題詞] Deoxyribonucleases,Type III Site-Specific
[英文釋義] Enzyme systems composed of two subunits and requiring ATP and magnesium for endonucleolytic activity; they do not function as ATPases. They exist as complexes with modification methylases of similar specificity listed under EC 2.1.1.72 or EC 2.1.1.73. The systems recognize specific short DNA sequences and cleave a short distance,about 24 to 27 bases,away from the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.5.